Video: Scientists have developed a new theory of aging
2024 Author: James Gerald | [email protected]. Last modified: 2023-12-17 14:00
The question "Is rejuvenation possible?" has been tormenting humanity for centuries. Scientists are desperately trying to invent an elixir of youth, or at least postpone the onset of old age. For the past few years, science has been dominated by the assumption that free radicals are to blame for the aging of the body, but a number of experts believe that the theory is already outdated.
For four decades, the prevailing interpretation of the aging process has been tied to so-called oxidative stress. According to this theory, free radicals, oxygen ions and peroxides accumulate in cells, gradually destroying them. Antioxidant drugs have been proposed as a means of fighting free radicals. However, now scientists have a slightly different point of view.
New data from Canadian researchers indicate an inverse relationship: the lifespan of some organisms with a partially impaired ability to resist the accumulation of free radicals does not decrease, but increases.
“The problem with the theory is that it is based only on the correlation of two events, the body of evidence,” explains Siegfried Hekimi of McGill University. - Indeed, the older the body, the more it suffers from oxidative stress. Due to this, the indicated hypothesis was strengthened: people take correlation for a cause-and-effect relationship."
According to experts, some organisms live longer, even when their ability to self-purify from oxidants is partially lost. After researching the worms Caenorhabditis elegans, scientists have concluded that mitochondrial activity is a key factor determining lifespan. Indeed, damage to them by active oxygen particles led to an increase in the life span of worms. At the same time, the researchers believe that active oxygen is not the cause of aging.
However, it would be a big mistake to think that oxidative stress has a positive effect on the body. “Free radicals certainly harm us. We only showed that they are probably not associated with aging,”warned Dr. Hekimi.
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