What hormonal drugs to take after 45 years

2024 Author: James Gerald | [email protected]. Last modified: 2024-01-12 17:37

Hormones are present in the body of every person and are designed to regulate its work. Most of them are produced in the endocrine glands. Synthetic hormones are artificial analogs of natural ones. Their use in the treatment of gynecological diseases gives tangible results. We will tell you what hormonal drugs to take after 45 years with menopause in order to get pregnant, as well as when losing weight.

What hormonal drugs to take after 45 years with menopause

After 45 years, every woman experiences global changes associated with hormonal changes in the body. A decrease in the production of female sex hormones (estrogens) leads to inhibition of the functionality of the reproductive system.

This is due to the fact that the ovaries gradually stop working. In this case, a woman loses the ability to conceive, after which her menstruation gradually disappears.

During menopause, many women after 45 years of age develop health problems due to a deficiency of sex hormones in the body. As a result, climacteric syndrome may develop, proceeding with varying degrees of severity. In such cases, hormone replacement therapy is indicated.

The action of drugs should primarily be aimed at regulating the level of estrogen in the blood. It is this hormone that is responsible for the general health of a woman:

• participates in the work of the circulatory system;
• reduces the risk of heart disease and atherosclerosis;
• prevents the leaching of calcium from the body;
• helps to maintain the elasticity of the skin;
• restores joint tissue.

Most often, women are prescribed drugs containing progesterone and estrogens. This takes into account: the age of the patient, her lifestyle, tendency to bad habits, the duration of menopause, diseases of the digestive system, the risk of cardiovascular disorders, as well as concomitant symptoms.

Applied means:

Femoston. Combined hormonal preparation, which contains dydrogesterone and estradiol - analogs of sex hormones. Available in film-coated tablets. The drug is effective in the occurrence of psychoemotional climacteric disorders: it reduces nervous excitability, relieves headache, promotes sleep recovery, eliminates mucosal dryness, and reduces the likelihood of endometrial hyperplasia

Divina. Hormone replacement drug. The main components: a derivative of progesterone and estradiol valerate. Able to maintain the activity of the reproductive system, bringing it closer to natural. Reduces the production of sweat glands, prevents atherosclerosis, lowers blood cholesterol levels, and reduces the risk of osteoporosis

Cyclo-Proginova. Anti-climacteric agent containing active ingredients: norgestrel, estradiol valerate and excipients: lactose, starch, magnesium stearate, talc. It allows you to delay the cessation of menstruation, prevents the suppression of ovulation, and stimulates the production of its own hormones. Estradiol compensates for the lack of estrogen in the body, provides treatment for autonomic disorders. Reduces sweating, normalizes sleep, has a calming effect, prevents skin involution, promotes bone tissue restoration, reduces muscle, joint and headache

This is not a complete list of drugs, it is presented solely for information. And the appointment of a specific medicine and its dosage can only be prescribed by a doctor. After 45 years, women with menopause can be assigned:

• Three regolas;
• Klimonorm;
• Femoston Conti;
• Divigel;
• Norkolut;
• Flutapharm;
• Marvelon and several others.

For substitution therapy, drugs are selected on a case-by-case basis. Contraindications to HRT are: breast cancer, cirrhosis, hepatitis, liver tumor, venous thrombosis, individual intolerance to certain components.

What hormonal drugs to take after 45 years for weight loss

From the age of 45, menopause occurs in women, the manifestations of which are accompanied by such unpleasant symptoms as hot flashes, ebb flushes, sleep disturbances, depression and deterioration of mood. In addition, hormonal imbalance leads to the fact that a woman begins to get better, seemingly for no apparent reason.

Small physical activity and restraint in nutrition no longer lead to the desired result. In the body, a redistribution of subcutaneous fat occurs, it begins to accumulate on the abdomen and be deposited on the thighs.

Metabolic disorders are often accompanied by rapid weight gain. Deficiency of estrogen during menopause leads to insulin resistance and changes in the composition of blood lipoproteins.

Estrogen, progesterone, and testosterone levels are most closely related to weight gain in menopausal women. These hormones are responsible for the development and condition of the breasts and hips.

Despite the fact that during menopause there is a decrease in estrogen, its prevalence over progesterone can cause the formation of body fat. To regulate the balance, women are prescribed hormonal medications.

This therapy can prevent weight gain. Research Needed for Prescribing Treatment:

• FSH analysis;
• mammography;
• oncocytology;
• Ultrasound of the breast and pelvic organs;
• caulogram.

Contraindications to HRT for weight gain are uterine cancer and breast cancer. In all other cases, an individual approach to solving the problem is assumed.

Hormonal drugs that can help prevent obesity during menopause:

Utrozhestan. The drug, the main component of which is micronized progesterone. Intended for oral use. Contains excipients: lecithin, sunflower oil, glycerin, gelatin, titanium dioxide. It is prescribed in a complex of substitution therapy during menopause, as well as for menstrual irregularities, infertility, PMS. Promotes the formation of a normal mucous membrane of the body of the uterus, accelerates the utilization of sugar in the blood, normalizes metabolic processes. Androgenically inactive

Dufaston. A medicine containing a progestogen, an analogue of progesterone. It is prescribed for endogenous deficiency of this hormone. The active ingredient is progestogen, which is able to replace it with regular use. Acts on the mucous membrane of the endometrium and cervical canal, without oppressing the ovaries. The drug helps to normalize hormonal balance and prevents the development of obesity in the postmenopausal period

Dexamethasone. It belongs to the group of glucocorticoid hormones. The drug has a pronounced effect on fat metabolism, regulates energy metabolism, induces protein compounds, and normalizes water-electrolyte balance. It affects all tissues of the body at the cellular level, since glucocorticoids are readily soluble in lipids and penetrate into cells through membranes. It is prescribed for endocrine disorders

Hormone replacement therapy helps to avoid abrupt changes in the female body, reduces the risk of breast cancer, heart attack and stroke. This is only a small part of the drugs. All appointments and doses must be prescribed by a doctor.

With an integrated approach to the problem, you can achieve much more effective results. Therefore, we must not forget about proper nutrition and physical activity.

Hormonal drugs after 45 years with endometriosis

Endometriosis is a common disease of the female reproductive system, characterized by the proliferation of endometrial cells. Among the clinical manifestations, they note: pain, the presence of discharge before menstruation, a violation of the cycle.

A complication of endometriosis can be the development of polycystic ovary disease and infertility. The treatment option for the disease is selected depending on the nature of its course and the degree of neglect of the process.

A pronounced therapeutic effect is achieved through the use of combined hormone therapy. Birth control pills may be prescribed to relieve pelvic pain.

Contraceptives are the best option for women who are not planning a pregnancy. The drugs have a minimum of contraindications and side effects, are acceptable for long-term therapy and are relatively inexpensive.

For endometriosis, progestogens are used:

• Norkolut;
• Duphaston;
• Levonorgestrel;
• MPA.

Hormones are prescribed at different stages of endometriosis. In this case, the course of treatment involves continuous admission and is about six months.

Progesterones take part in ensuring fertilization, contribute to the normalization of the endometrium and the transition of the mucous membrane to an optimal state for the development of the egg after conception.

Side effects: depression, spotting, increased sensitivity of the mammary glands.

Antigonadotropins may also be prescribed:

• Danol;
• Danazol and a number of others.

Drugs of this group inhibit the activity of the ovaries and promote endometrial atrophy with a reversible effect, relieve pain. Antigonadotropes have no estrogenic effect and inhibit lymphocyte proliferation.

With mastopathy, they contribute to the disappearance of seals and a decrease in pain. The effect is achieved with a course of treatment lasting 6 months. Release hormone agonists:

• Goserelin;
• Tripotrelin.

Medicines reduce the level of estrogen in the body and help suppress ovulation. Their advantage is the absence of side effects.

What hormonal drugs to take after 45 years to get pregnant

Having a baby after 45 is much more difficult than at a younger age. During the menopausal period, reproductive function in women begins to gradually fade away. The ovaries produce fewer eggs and the chances of getting pregnant are reduced.

But the onset of menopause does not happen instantly. Until the body has lost the ability to ovulate, conception can be planned. To control the situation, expectant mothers are advised to regularly visit a gynecologist. In many cases, hormones come to the rescue.

Taking contraceptives during intercourse after 45 years of age increases the chances of safely enduring pregnancy. Temporary cessation of menstruation does not necessarily indicate the onset of menopause. It can be due to amenorrhea, which makes it much easier to get pregnant.

Hormonal infertility at the age of 45-50 is eliminated by taking medication. Therapy in such cases should be aimed at normalizing hormonal levels and maintaining reproductive function in the female body.

Genetically engineered gonadotropins are used. The pharmacology of the drugs is identical to the HMG menotropins, however, they show greater efficiency and contain luteinizing and follicle-stimulating hormones in their pure form.

In the treatment of infertility, women after 45 years of age may be prescribed hormone-containing medications:

• Clomid;
• MCG Massone;
• Metriofet;
• Menopur;
• HuMog;
• Menopur Multi-dose.

Indications for their use: primary or secondary amenorrhea, infertility, growth retardation of the dominant follicle, hypomenstrual syndrome, ovarian dysfunction, Chiari-Frommel syndrome.

Treatment of infertility with hormonal drugs is effective for endocrine disorders with the absence of adhesions in the fallopian tubes. If the reason for the inability to conceive a child after 45 years is an inflammatory process, antibiotics are used. Most often, Metrogyl or Ciprofloxacin is prescribed.

The choice of treatment tactics is carried out in each case individually and depends on factors such as the patient's age, the causes of hormonal disorders, the presence of concomitant diseases. All appointments must be made by the attending physician.

The information about the drugs presented in the article is for informational purposes only.